large noncleaved cell

large noncleaved cell
large noncleaved follicular center cell, large uncleaved cell a follicular center cell considered to be the stage immediately preceding the development of the B lymphoblast and migration out of the follicle; it has a diameter of 15–20 μm, a nucleus without clefts that contains finely dispersed chromatin, and cytoplasm that is abundant and pyroninophilic.

Medical dictionary. 2011.

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  • large noncleaved cell lymphoma — a type of non Hodgkin lymphoma characterized by formation of malignant large noncleaved follicular center cells. Because of the wide variety of prognostic levels and the existence of tumors with several types of cells, these tumors have been… …   Medical dictionary

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