focal adhesion

focal adhesion
a specialized area of the plasma membrane, characterized by clusters of integrins that transduce transmembrane signals and link actin filaments of the cytoskeleton to the extracellular matrix. Called also focal contact.

Medical dictionary. 2011.

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  • Focal adhesion — In cell biology, focal adhesions (also cell matrix adhesions or FAs) are specific types of large macromolecular assemblies through which both mechanical force and regulatory signals are transmitted. More precisely, they can be considered as sub… …   Wikipedia

  • Focal adhesion — Immunfluoreszenzfärbung des Aktin Zytoskeletts (grün) und des fokalen Adhäsionsproteins Vinculin (rot) bei einer Fibroblasten Zelle. Die Adhäsionsstellen sind als rote Flecken an den Enden der Aktin Bündel erkennbar. Fokale Adhäsionen (engl.… …   Deutsch Wikipedia

  • Focal adhesion kinase — (FAK) is a focal adhesion associated protein kinase involved in cellular adhesion and spreading processes. [Lackie, J.M. Dow, J.A.T., The Dictionary of Cell and Molecular Biology, 3rd Edition, Academic Press, London, 1999] It is used by cells to… …   Wikipedia

  • Focal adhesion kinase — Pour les articles homonymes, voir FAK. La Focal Adhesion Kinase (FAK) est une protéine dite ubiquitaire, c est à dire qu on la retrouve dans presque tous les types cellulaires. Sommaire 1 Description 2 Domaines …   Wikipédia en Français

  • focal adhesion kinase — Protein kinase which is found at focal adhesionsand is thought to mediate the adhesion or spreading processes …   Dictionary of molecular biology

  • focal contact — focal adhesion …   Medical dictionary

  • Focal — may refer to:*Focal (lexicographical website), an Irish lexicographical website *FOCAL (programming language) **FOCAL 69 **Focal (HP 41) *Relating to focusee also*Focal point (disambiguation) *Focal adhesion *Focal character *Focal dystonia… …   Wikipedia

  • Adhesion (disambiguation) — Adhesion is the tendency of certain dissimiliar molecules to cling together.Adhesion may also refer to:; In life sciences and medicine*Adhesion (medicine), a fibrous band that forms between tissues and organs *Cell adhesion, the binding of a cell …   Wikipedia

  • adhesion plaque — Another term for a focal adhesion, a discrete area of close contact between a cell and a non cellular substratum, with cytoplasmic insertion of microfilaments and considerable electron density adjacent to the contact area. On the cytoplasmic face …   Dictionary of molecular biology

  • Cell adhesion — Cellular adhesion is the binding of a cell to a surface, extracellular matrix or another cell using cell adhesion molecules such as selectins, integrins, and cadherins. Correct cellular adhesion is essential in maintaining multicellular structure …   Wikipedia

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