sphingomyelin phosphodiesterase
- sphingomyelin phosphodiesterase
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sphin·go·my·elin phos·pho·di·es·ter·ase (sfing″go-miґə-lin fos″fo-di-esґtər-ās) [EC 3.1.4.12] an enzyme of the hydrolase class that catalyzes the cleavage of sphingomyelin to ceramide and phosphorylated choline in the major pathway for sphingomyelin degradation. Deficiency of the enzyme, an autosomal recessive trait, causes Niemann-Pick disease. Called also sphingomyelinase.
Medical dictionary.
2011.
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Sphingomyelin phosphodiesterase — Sphingomyelinase phosphodiesterase or simply Sphingomyelinase (SMase) is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking… … Wikipedia
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