neuraminidase

neuraminidase
SYN: sialidase.

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neur·amin·i·dase .n(y)u̇r-ə-'min-ə-.dās, -.dāz n a hydrolytic enzyme that occurs on the surface of the pneumococcus, the orthomyxoviruses, and some paramyxoviruses and that cleaves terminal acetylated neuraminic acids from sugar residues (as in glycoproteins and mucoproteins)

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neu·ra·min·i·dase (noor″ə-minґĭ-dās) an enzyme of the hydrolase class that catalyzes the cleavage of glucosidic linkages between a sialic acid residue and a hexose or hexosamine residue at the nonreducing terminal of oligosaccharides in glycoproteins, glycolipids, and proteoglycans. Cytosolic, plasma membrane, and lysosomal forms of the enzyme exist; deficiency of the latter, an autosomal recessive trait, causes sialidosis; enzyme activity is also lacking in galactosialidosis. Viral neuraminidase found on the surface of influenza viruses enables viral release from the host cell. In EC nomenclature, called exo-α-sialidase. Called also sialidase.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Neuraminidase — Bezeichner Gen Namen …   Deutsch Wikipedia

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  • Neuraminidase — Pour les articles homonymes, voir N1, N2, N3, N4, N5, N6, N7, N8 et N9 …   Wikipédia en Français

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  • Neuraminidase inhibitor — Neuraminidase inhibitors are a class of antiviral drugs targeted at the influenza virus, which work by blocking the function of the viral neuraminidase protein, thus preventing the virus from reproducing by budding from the host cell. Oseltamivir …   Wikipedia

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  • Neuraminidase-β-Galaktosidase-Mangel — Klassifikation nach ICD 10 E77.8 Sonstige Störungen des Glykoproteinstoffwechsels …   Deutsch Wikipedia

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