homogentisic acid oxidase

homogentisic acid oxidase
ho·mo·gen·tis·ic ac·id ox·i·dase (ho″mo-jen-tisґik asґid okґsĭ-dās) homogentisate 1,2-dioxygenase.

Medical dictionary. 2011.

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  • homogentisic acid — Glycosuric acid; (2,5 dihydroxyphenyl)acetic acid; an intermediate in l phenylalanine and l tyrosine catabolism; if made alkaline, it oxidizes rapidly in air to a quinone that polymerizes to a melaninlike material; elevated levels are observed in …   Medical dictionary

  • homogentisic acid — a product formed during the metabolism of the amino acids phenylalanine and tyrosine. In normal individuals homogentisic acid is oxidized by the enzyme homogentisic acid oxidase. In rare cases this enzyme is lacking and a condition known as… …   The new mediacal dictionary

  • homogentisic acid oxidase deficiency — ho·mo·gen·tis·ic ac·id ox·i·dase de·fi·cien·cy (ho″mo jen tisґik asґid okґsĭ dās) alkaptonuria …   Medical dictionary

  • Кислота Гомогентизиновая (Homogentisic Acid) — вещество, образующееся во время метаболизма аминокислот фенилаланина и тирозина. У нормальных, здоровых индивидуумов гомогентизиновая кислота окисляется с помощью фермента оксидазы гомогентизиновой кислоты (homogentisic acid oxidase). В редких… …   Медицинские термины

  • maleylacetoacetic acid — noun A chemical compound formed from the oxidation of homogentisic acid oxidase and isomerized into fumarylacetoacetic acid …   Wiktionary

  • КИСЛОТА ГОМОГЕНТИЗИНОВАЯ — (homogentisic acid) вещество, образующееся во время метаболизма аминокислот фенилаланина и тирозина. У нормальных, здоровых индивидуумов гомогентизиновая кислота окисляется с помощью фермента оксидазы гомогентизиновой кислоты (homogentisic acid… …   Толковый словарь по медицине

  • Alkaptonuria — Infobox Disease Name = PAGENAME Caption = Homogentisic acid Width = 180 DiseasesDB = 409 ICD10 = ICD10|E|70|2|e|70 ICD9 = ICD9|270.2 ICDO = OMIM = 203500 MedlinePlus = eMedicineSubj = ped eMedicineTopic = 64 MeshID = D000474 Alkaptonuria (black… …   Wikipedia

  • heredity — /heuh red i tee/, n., pl. heredities. Biol. 1. the transmission of genetic characters from parents to offspring: it is dependent upon the segregation and recombination of genes during meiosis and fertilization and results in the genesis of a new… …   Universalium

  • connective tissue disease — Introduction       any of the diseases that affect human connective tissue. Diseases of the connective tissue can be divided into (1) a group of relatively uncommon genetic disorders (genetic disease, human) that affect the primary structure of… …   Universalium

  • alkaptonuria — Congenital absence of homogentisic acid oxidase, an enzyme that breaks down tyrosine and phenylalanine. Accumulation of homogentisic acid in homozygotes causes brown pigmentation of skin and eyes and damage to joints; urine blackens on standing …   Dictionary of molecular biology

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