entacapone

entacapone
en·tac·a·pone (en-takґə-pōn) a selective, reversible inhibitor of catechol O-methyltransferase, the enzyme mainly responsible for levodopa metabolism in the brain and periphery in the presence of carbidopa; used in conjunction with levodopa and carbidopa to enhance dopaminergic stimulation of the brain and the antiparkinsonian activity of levodopa in the treatment of idiopathic Parkinson disease, administered orally.

Medical dictionary. 2011.

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