Donath-Landsteiner antibody test
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Donath-Landsteiner test — (for paroxysmal cold hemoglobinuria) a test based on the fact that the blood of patients with this disease contains complement dependent iso and autohemolysin (Donath Landsteiner antibody) which unites with red cells only at low temperatures (2°… … Medical dictionary
test — 1. To prove; to try a substance; to determine the chemical nature of a substance by means of reagents. 2. A method of examination, as to determine the presence or absence of a definite disease or of some substance in any of the fluids, tissues,… … Medical dictionary
paroxysmal cold hemoglobinuria — an autoimmune or postviral disease marked by episodes of hemoglobinemia and hemoglobinuria after exposure to cold, caused by complement dependent hemolysis due to IgG antibody (Donath Landsteiner antibody) directed against the P blood group… … Medical dictionary
Autoagglutination — represents clumping of an individual s red blood cells (RBCs or erythrocytes) by his or her own serum due to the RBCs being coated on their surface by antibodies.Autoagglutination is seen to occur in a type of immune mediated hemolytic anemia… … Wikipedia
phenomenon — 1. A symptom; an occurrence of any sort, whether ordinary or extraordinary, in relation to a disease. 2. Any unusual fact or occurrence. [G. phainomenon, fr. phaino, to cause to appear] adhesion p. a p. manifested by the adherence of antigen… … Medical dictionary
