subacute combined degeneration of spinal cord

subacute combined degeneration of spinal cord
neurodegeneration involving both the posterior and lateral columns of the spinal cord, caused by vitamin B12 deficiency; a progressive disease, most often affecting persons over forty years of age, it is usually associated with pernicious anemia. The symptoms include paresthesias, ataxia, unsteadiness of gait, and sometimes emotional disorders. Called also combined system disease, combined sclerosis, Lichtheim disease or syndrome, Putnam-Dana syndrome, and posterolateral sclerosis.

Medical dictionary. 2011.

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  • Subacute combined degeneration of spinal cord — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 12591 ICD10 = ICD10|G|32|0|g|30, ICD10|E|53|8|e|50 ICD9 = ICD9|336.2, ICD9|266.2 ICDO = OMIM = MedlinePlus = 000723 eMedicineSubj = eMedicineTopic = MeshID = D052879 Subacute combined… …   Wikipedia

  • subacute combined degeneration of the cord — the neurological disorder complicating a deficiency of vitamin B12 and pernicious anaemia. There is selective damage to the motor and sensory nerve fibres in the spinal cord, resulting in spasticity of the limbs and a sensory ataxia. It may also… …   Medical dictionary

  • subacute combined degeneration of the cord — the neurological disorder complicating a deficiency of vitamin B 12 and pernicious anaemia, which causes malabsorption of the vitamin B12 by the production of intrinsic factor antibodies. There is selective damage to the motor and sensory nerve… …   The new mediacal dictionary

  • combined system disease — subacute combined degeneration of spinal cord; see under degeneration …   Medical dictionary

  • combined sclerosis — subacute combined degeneration of spinal cord; see under degeneration …   Medical dictionary

  • degeneration — 1. Deterioration; passing from a higher to a lower level or type. 2. A worsening of mental, physical, or moral qualities. 3. A retrogressive pathologic change in cells or tissues, in consequence of which their functions are often impaired or… …   Medical dictionary

  • ataxic paraplegia — subacute combined degeneration of spinal cord; see under degeneration …   Medical dictionary

  • posterolateral sclerosis — subacute combined degeneration of spinal cord; see under degeneration …   Medical dictionary

  • Lichtheim syndrome — subacute combined degeneration of spinal cord; see under degeneration …   Medical dictionary

  • Putnam-Dana syndrome — subacute combined degeneration of spinal cord (see under degeneration) …   Medical dictionary

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