cystathionine γ-lyase

cystathionine γ-lyase
cys·ta·thi·o·nine γ-ly·ase (sis″tə-thiґo-nēn liґās) [EC 4.4.1.1] an enzyme of the lyase class that catalyzes the cleavage of cystathionine to cysteine, α-ketoglutarate, and ammonia as a step in the metabolism of methionine. It is a pyridoxal-phosphate protein and the reaction occurs in the liver. Deficiency of the enzyme, an autosomal recessive trait, results in cystathioninuria. Called also γ-cystathionase.

Medical dictionary. 2011.

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