corticosterone 18-monooxygenase

corticosterone 18-monooxygenase
cor·ti·cos·ter·one 18-mono·oxy·ge·nase (kor″tĭ-kosґtər-ōn mon″o-okґsə-jən-ās) [EC 1.14.15.5] an enzyme of the oxidoreductase class that catalyzes hydroxylation of corticosteroids at the 18 position followed by oxidation of the 18-hydroxy intermediates, steps in the biosynthesis of aldosterone. The two reactions are sometimes considered separately as I (hydroxylation) and II (oxidation); defects in each reaction have been described and called corticosterone methyl oxidase deficiency, types I and II. The enzyme may be an activity of steroid 11β-monooxygenase (q.v.)

Medical dictionary. 2011.

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  • Corticosterone 18-monooxygenase — Identifiers EC number 1.14.15.5 CAS number 37256 75 0 …   Wikipedia

  • corticosterone methyl oxidase — cor·ti·cos·ter·one meth·yl ox·i·dase (kor″tĭ kosґtər ōn methґəl okґsĭ dās) corticosterone 18 monooxygenase …   Medical dictionary

  • steroid 11β-monooxygenase — ster·oid 11β mono·oxy·gen·ase (sterґoid mon″o okґsə jən ās) [EC 1.14.15.4] an enzyme of the oxidoreductase class that catalyzes the NADPH dependent hydroxylation of steroids at the 11 position as a step in the synthesis… …   Medical dictionary

  • 18-hydroxylase — corticosterone 18 monooxygenase; sometimes specifically the enzyme activity catalyzing the first (hydroxylation) reaction …   Medical dictionary

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • aldosterone synthase — al·dos·ter·one syn·thase (al dosґtər ōn sinґthās) an isozyme of steroid 11β monooxygenase that catalyzes the last three steps (11 hydroxylation, 18 hydroxylation, and 18 oxidation) in the synthesis of aldosterone from… …   Medical dictionary

  • 18-hydroxysteroid dehydrogenase — 18 hy·droxy·ste·roid de·hy·dro·gen·ase (hi drok″se sterґoid de hiґdro jən ās) the enzyme activity of corticosterone 18 monooxygenase specifically catalyzing the second (oxidation) reaction. Deficiency of this enzyme activity is… …   Medical dictionary

  • CMO — is a three letter abbreviation that may stand for: Contents 1 Engineering 2 Entertainment 3 Health 4 Marketing 5 …   Wikipedia

  • Steroid 11-beta-hydroxylase — Cytochrome P450, family 11, subfamily B, polypeptide 1 Identifiers Symbols CYP11B1; CPN1; CYP11B; DKFZp686B05283; FHI; FLJ36771; P450C11 External IDs …   Wikipedia

  • Tyrosine — NatOrganicBox name=( S ) 2 Amino 3 (4 hydroxyphenyl) propanoic acid PubChem = 1153 CAS = 60 18 4 SMILES = N [C@@H] (Cc1ccc(O)cc1)C(O)=O C=9 | H=11 | N=1 | O=3 mass=181.19 g/molTyrosine (abbreviated as Tyr or Y) [cite web | author=IUPAC IUBMB… …   Wikipedia

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