azole antifungal

azole antifungal
any of a group of antifungals characterized by the presence of an azole ring structure, which includes the triazoles and the imidazoles (qq.v.). They are usually fungistatic but can be fungicidal at higher concentrations, and act by interfering with the enzyme activity of cytochrome P-450, decreasing the production of ergosterol and so damaging the cell membrane by altering its permeability and functions.

Medical dictionary. 2011.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • Azole — An azole is a class of five membered nitrogen heterocyclic ring compounds containing at least one other non carbon atom of either nitrogen, sulfur, or oxygen.[1] The parent compounds are aromatic and have two double bonds; there are successively… …   Wikipedia

  • azole — SYN: pyrrole. * * * azole ā .zōl, az .ōl n any of numerous compounds characterized by a 5 membered ring containing at least one atom of nitrogen * * * az·ole (azґōl) 1. any of a group of organic compounds containing a five membered… …   Medical dictionary

  • Ketoconazole — Systematic (IUPAC) name 1 [4 (4 {[(2R,4 …   Wikipedia

  • Itraconazole — Systematic (IUPAC) name (2R,4S) rel 1 (butan 2 yl) 4 {4 [4 (4 {[(2R,4S) 2 (2,4 dichlorophenyl) 2 (1H 1,2,4 triazol 1 ylmethyl) 1,3 dioxolan 4 yl]methoxy}phenyl)piperazin 1 yl]phenyl} 4,5 dihydro 1H 1,2,4 …   Wikipedia

  • Voriconazole — drugbox IUPAC name = (2 R ,3 S ) 2 (2,4 difluorophenyl) 3 (5 fluoropyrimidin 4 yl) 1 (1 H 1,2,4 triazol 1 yl) butan 2 ol CAS number = 137234 62 9 ATC prefix = J02 ATC suffix = AC03 ATC supplemental = PubChem = 71616 DrugBank = APRD00543 C=16 |… …   Wikipedia

  • PGRMC1 — Progesterone receptor membrane component 1 (abbreviated PGRMC1) is a protein which co purifies with progesterone binding proteins in the liver and ovary.cite journal | author = Meyer C, Schmid R, Scriba PC, Wehling M | title = Purification and… …   Wikipedia

  • Omoconazole — Systematic (IUPAC) name 1 [(Z) 2 [2 (4 chlorophenoxy)ethoxy] 2 (2,4 dichlorophenyl) 1 methylvinyl] 1H imidazole Clinical data AHFS/ …   Wikipedia

  • Fenticonazole — drugbox IUPAC name = 1 (2 (2,4 dichlorophenyl) 2 (4 (phenylthio)benzyloxy)ethyl) 1H imidazole CAS number = 72479 26 6 ATC prefix = D01 ATC suffix = AC12 ATC supplemental = ATC|G01|AF12 PubChem = 51755 DrugBank = C=24|H=20|Cl=2|N=2|O=1|S=1… …   Wikipedia

  • Isoconazole — drugbox IUPAC name = 1 (2 (2,6 dichlorobenzyloxy) 2 (2,4 dichlorophenyl)ethyl) 1H imidazole CAS number = 27523 40 6 ATC prefix = D01 ATC suffix = AC05 ATC supplemental = ATC|G01|AF07 PubChem = 3760 DrugBank = C=18|H=14|Cl=4|N=2|O=1 molecular… …   Wikipedia

  • Chlormidazole — Systematic (IUPAC) name 1 [(4 chlorophenyl)methyl] 2 methyl 1H 1,3 benzodiazole Clinical data AHFS/Drugs.com …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”